Open-source protein structure AI aims to match AlphaFold image

OpenFold3: New Open-Source AI Challenges AlphaFold in Protein Structure Prediction

Date: Oct 29, 2025

Category: Science & Technology


A groundbreaking open-source artificial intelligence (AI) model, OpenFold3, has been unveiled by its developers, marking a significant leap forward in protein structure prediction. Designed to compete with DeepMind’s renowned AlphaFold, OpenFold3 provides researchers and scientists with a freely accessible tool for modeling complex protein structures. The early release of OpenFold3 showcases its ability to predict how proteins interact with other molecules, such as RNA, mirroring the advanced capabilities of AlphaFold3. This innovation is expected to accelerate discoveries in drug development, molecular biology, and biotechnology by democratizing access to state-of-the-art protein modeling technology. The OpenFold3 project emphasizes transparency and collaboration, inviting the global scientific community to contribute to its ongoing development. As the tool evolves, its creators hope it will match—and potentially surpass—the accuracy and performance of proprietary models like AlphaFold, fostering rapid advancements in life sciences and medical research. Read the source »

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