Date: Nov 18, 2025
Category: Health & Technology
Recent research has unveiled how obesity medications such as Mounjaro (tirzepatide) and Ozempic target the brain to reduce compulsive food cravings—a phenomenon often referred to as 'food noise.' These drugs act on GLP-1 receptors in the brain, which play a crucial role in regulating appetite and satiety. A team of neuroscientists has identified a specific neural biomarker associated with compulsive food cravings. Their findings show that this biomarker is significantly suppressed when patients use GLP-1 receptor agonists like Mounjaro. This suppression translates to a dramatic reduction in intrusive thoughts about food, making it easier for individuals to resist overeating and adhere to healthier eating habits. The study, published in a leading medical journal, involved brain imaging of participants before and after treatment with tirzepatide. The results revealed measurable decreases in neural activity linked to food cues, providing direct evidence of how these medications alter brain function to support weight loss. These insights not only deepen our understanding of how obesity drugs work at the neurological level but also open the door to more targeted therapies for those struggling with compulsive eating. As the prevalence of obesity continues to rise globally, such breakthroughs could pave the way for more effective and personalized treatment strategies. Read the source »
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